Cycling in Giro d'Italia | _pictogram.svg) | ||||
| 2024 |  | ITA | Elisa Longo Borghini | |
| 2023 |  | NED | Annemiek van Vleuten | |
| 2022 | | NED | Annemiek van Vleuten | |
| 2021 | | NED | Anna van der Breggen | |
| 2020 | | NED | Anna van der Breggen | |
| 2019 | | NED | Annemiek van Vleuten | |
| 2018 | | NED | Annemiek van Vleuten | |
| 2017 | | NED | Anna van der Breggen | |
| 2016 |  | USA | Megan Guarnier | |
| 2015 | | NED | Anna van der Breggen | |
| 2014 | | NED | Marianne Vos | |
| 2013 | | USA | Mara Abbott | |
| 2012 | | NED | Marianne Vos | |
| 2011 | | NED | Marianne Vos | |
| 2010 | | USA | Mara Abbott | |
| 2009 |  | GER | Claudia Lichtenberg | |
| 2008 | | ITA | Fabiana Luperini | |
| 2007 |  | LTU | Edita Pucinskaite | |
| 2006 | | LTU | Edita Pucinskaite | |
| 2005 |  | SUI | Nicole Brändli | |
| 2004 |  | GBR | Nicole Cooke | |
| 2003 | | SUI | Nicole Brändli | |
| 2002 |  | RUS | Svetlana Bubnenkova | |
| 2001 | | SUI | Nicole Brändli | |
| 2000 |  | ESP | Joane Somarriba | |
| 1999 | | ESP | Joane Somarriba | |
| 1998 | | ITA | Fabiana Luperini | |
| 1997 | | ITA | Fabiana Luperini | |
| 1996 | | ITA | Fabiana Luperini | |
| 1995 | | ITA | Fabiana Luperini | |
| 1994 | | ITA | Michela Fanini | |
| 1993 |  | SVK | Lenka Ilavska | |
| 1990 |  | FRA | Catherine Marsal | |
| 1989 | | ITA | Roberta Bonanomi | |
| 1988 | | ITA | Maria Canins | |